ATE46146T1 - Phenylpiperidinderivat und seine salze, ihre herstellung, sie enthaltende zusammensetzungen und ihre therapeutische verwendung. - Google Patents

Phenylpiperidinderivat und seine salze, ihre herstellung, sie enthaltende zusammensetzungen und ihre therapeutische verwendung.

Info

Publication number
ATE46146T1
ATE46146T1 AT85300793T AT85300793T ATE46146T1 AT E46146 T1 ATE46146 T1 AT E46146T1 AT 85300793 T AT85300793 T AT 85300793T AT 85300793 T AT85300793 T AT 85300793T AT E46146 T1 ATE46146 T1 AT E46146T1
Authority
AT
Austria
Prior art keywords
salts
phenylpiperide
derivate
production
compositions containing
Prior art date
Application number
AT85300793T
Other languages
German (de)
English (en)
Inventor
Jorgen Buus Lassen
Jorgen Anders Christensen
Erling Niels Petersen
John Bondo Hansen
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Application granted granted Critical
Publication of ATE46146T1 publication Critical patent/ATE46146T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT85300793T 1984-02-07 1985-02-06 Phenylpiperidinderivat und seine salze, ihre herstellung, sie enthaltende zusammensetzungen und ihre therapeutische verwendung. ATE46146T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/577,844 US4585777A (en) 1984-02-07 1984-02-07 (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT
EP85300793A EP0152273B1 (en) 1984-02-07 1985-02-06 A phenylpiperidine derivative, and its salts, their preparation, compositions containing them, and their therapeutic use

Publications (1)

Publication Number Publication Date
ATE46146T1 true ATE46146T1 (de) 1989-09-15

Family

ID=24310381

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85300793T ATE46146T1 (de) 1984-02-07 1985-02-06 Phenylpiperidinderivat und seine salze, ihre herstellung, sie enthaltende zusammensetzungen und ihre therapeutische verwendung.

Country Status (12)

Country Link
US (1) US4585777A (en])
EP (1) EP0152273B1 (en])
JP (1) JPS60181071A (en])
AT (1) ATE46146T1 (en])
CA (1) CA1246082A (en])
DE (1) DE3572807D1 (en])
DK (1) DK53285A (en])
ES (1) ES540172A0 (en])
FI (1) FI850449A7 (en])
GR (1) GR850309B (en])
IE (1) IE850286L (en])
NO (1) NO850444L (en])

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0223334B1 (en) * 1985-08-10 1991-07-10 Beecham Group Plc Process for the preparation of aryl-piperidine carbinols
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
GB8626936D0 (en) * 1986-11-11 1986-12-10 Ferrosan As Treatment
HU221921B1 (hu) * 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
GB9623359D0 (en) * 1996-11-09 1997-01-08 Smithkline Beecham Plc Novel process
GB9700690D0 (en) 1997-01-15 1997-03-05 Smithkline Beecham Plc Novel process
ID24383A (id) * 1997-05-29 2000-07-13 Smithkline Beecham Corp Proses baru
AU2002301956B2 (en) * 1997-06-10 2006-02-09 Synthon B.V. 4-phenylpiperidine compounds
HUP0003141A3 (en) * 1997-06-10 2001-04-28 Synthon Bv 4-phenylpiperidine derivatives, process for producing them and pharmaceutical compositions containing them
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
GB9914583D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
WO2001085688A1 (en) 2000-05-12 2001-11-15 Synthon B.V. TOSYLATE SALTS OF 4-(p-FLUOROPHENYL)-PIPERIDINE-3-CARBINOLS
US20040087795A1 (en) * 2000-07-17 2004-05-06 Borrett Gary Thomas Novel processes for the preparation of 4-phenylpiperidine derivatives
AU2001211337A1 (en) * 2000-10-06 2002-04-15 Smithkline Beecham Plc Process for the preparation of aryl-piperidine carbinols and intermediates thereof
US6777554B2 (en) 2001-02-05 2004-08-17 Teva Pharmaceutical Industries Ltd. Preparation of N-methylparoxetine and related intermediate compounds
NL1017421C2 (nl) * 2001-02-21 2002-01-15 Synthon Bv Werkwijze voor het vervaardigen van paroxetine.
CA2457382A1 (en) * 2001-06-13 2002-12-19 Teva Pharmaceutical Industries Ltd. Process for the preparation of paroxetine substantially free of alkoxy impurities
US20070142389A1 (en) * 2005-12-20 2007-06-21 Pfizer Inc. Piperidine derivatives
US8822498B2 (en) * 2007-09-13 2014-09-02 Concert Pharmaceuticals, Inc. Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds

Also Published As

Publication number Publication date
FI850449A0 (fi) 1985-02-04
FI850449L (fi) 1985-08-08
DE3572807D1 (en) 1989-10-12
EP0152273A2 (en) 1985-08-21
DK53285D0 (da) 1985-02-06
US4585777A (en) 1986-04-29
JPS6135176B2 (en]) 1986-08-12
FI850449A7 (fi) 1985-08-08
GR850309B (en]) 1985-06-05
EP0152273B1 (en) 1989-09-06
DK53285A (da) 1985-08-08
EP0152273A3 (en) 1986-12-30
JPS60181071A (ja) 1985-09-14
NO850444L (no) 1985-08-08
ES8601131A1 (es) 1985-11-16
ES540172A0 (es) 1985-11-16
IE850286L (en) 1985-08-07
CA1246082A (en) 1988-12-06

Similar Documents

Publication Publication Date Title
ATE46146T1 (de) Phenylpiperidinderivat und seine salze, ihre herstellung, sie enthaltende zusammensetzungen und ihre therapeutische verwendung.
UA27749C2 (uk) Заміщені циклопропіламіно-1,3,5-триазини, їх оптичні ізомери, рацемічні суміші чи їх солі приєднання нетоксичних фармацевтично прийнятних кислот, що мають фармакологічну активність, спосіб їх одержання (варіанти) та фармацевтична композиція на їх основі
NZ214611A (en) Piperazine derivatives and pharmaceutical compositions
FI810604L (fi) Foerfarande foer framstaellning av indanderivat
SE8703169D0 (sv) 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-3,4-dihydro-5h-2,3-benzodiazepine, acid addition salts thereof and process for preparing same
DE59208974D1 (de) Neue pyrazinderivative, ihre herstellung und verwendung
ATE91078T1 (de) Verwendung von melatonin oder seine derivate zur herstellung von arzneimitteln, die gegen alterskrankheiten wirksam sind.
AU6319480A (en) 2-hydroxyalkyl-3,4,5-trihydroxypiperidines
DE3586649D1 (de) Verwendung von spergualinderivaten zur herstellung von arzneimitteln mit immunodepressiver wirkung.
DK412985D0 (da) Prolinforbindelse og farmaceutisk praeparat indeholdende forbindelsen
DE59010865D1 (de) N-substituierte naphthalimide, ihre herstellung und verwendung
ATE70060T1 (de) Neue tetrahydro-benzothiazole, ihre herstellung und verwendung.
DE68919280D1 (de) Alpha-adrenergische Rezeptorantagonisten.
ATE15894T1 (de) Heterocyclische derivate von amidoxinen, ihre herstellung und therapeutische verwendung.
ES8608887A1 (es) Procedimiento para la obtencion de preparados combinados antihipertensores y antianginicos a base de dihidropiridina y bloquear beta.
ATE124398T1 (de) 1,3,4-trisubstituierte piperidin-derivate, ihre herstellung und verwendung.
ZW6889A1 (en) &-adrenergic receptor antagonists
FI905922A0 (fi) Antagonister foer a-adrenerga receptorer.
ATE155479T1 (de) Neue cytarabin-derivate, ihre herstellung und verwendung
DE3672635D1 (de) Esterderivate von 2,2-dimethyl-3-ethenylcyclopropancarbonsaeure, ihre herstellung, ihre verwendung als parasitizide und sie enthaltende zusammensetzungen.
ES480869A1 (es) Procedimiento de preparar derivados de xilita.
ATE7893T1 (de) 10b-carboxy-aminoborane, verfahren zur herstellung derselben sowie ihre verwendung als arzneimittel zur neutroneneinfangtherapie.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee